About
Physical Characteristics
Caps:
None
Gills:
None
Choosing the Right Products
• Look for content guarentees:
Polysaccharides can be misleading as starch is a polysaccharide. Many Lions Mane products are mycelium grown on grain. These supplements often contain large quantities of starches. Look for products that guarantee diterpine or erinacine content.
Cognitive Effects
Memory
Lion's Mane has been shown to potentially support memory and improve cognitive function. It may help enhance both short-term and long-term memory recall.
Focus
Some individuals report improved focus and mental clarity when supplementing with Lion's Mane. It may help enhance cognitive performance, increase alertness, and reduce mental fatigue.
Calm
Studies have shown that Lions Mane may have positive effects on mood and emotional well-being. It is believed to support a healthy stress response and may help reduce symptoms of anxiety and depression.
Helps With
Dementia
Shown to enhance nerve growth and alleviate symptoms of neurodegenerative diseases
Alzheimers
Shown to enhance nerve growth and alleviate symptoms of neurodegenerative diseases
Immune System
Boosts immune system through its antioxidant capabilities
Digestion
Reduces inflammation and supports overall gut health
Stress
Lion's Mane may have positive effects on mood and emotional well-being. It is believed to support a healthy stress response and may help reduce symptoms of anxiety and depression.
Inflamation
Lion's Mane has anti-inflammatory properties and may help reduce inflammation in the body. It is believed to support the immune system and promote overall health and well-being.
Ulcers
Lion's Mane mushroom supports the gut and promotes a sense of calm while preparing the body for a good night's rest.
Insomnia
Lion's Mane mushroom supports the gut and promotes a sense of calm while preparing the body for a good night's rest.
Fertility
This mushroom is believed to support reproductive wellness and hormonal balance.
Gut Microbiome
Known anti-inflammatory properties that can help reduce gut inflammation, beneficial for individuals with IBD and other gut disorders. Moreover, Lion's Mane mushrooms can enhance the integrity of the gut lining, reducing the risk of leaky gut syndrome.
Look Alike Species
Specie: | Differences: | |
|---|---|---|
 | Hericium coralloides Edibility:edible | Hericium coralloides has more of a coral-like structure, while Hericium erinaceus has long spines giving it a shaggy appearance. |
Specie:
Hericium coralloides
Edibility:
edible
Differences:Hericium coralloides has more of a coral-like structure, while Hericium erinaceus has long spines giving it a shaggy appearance.
Nutrition Facts (Raw)
Mushroom Ratings
4.5
Based on 2 Reviews
5
★4
★3
★2
★1
★Zack Mooney
4
07/18/2024
Zack Mooney
5
07/10/2024
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5
References
Isolation and Evaluation of Erinacine A Contents in Mycelia of Hericium erinaceus Strains
Effect of erinacine A-enriched Hericium erinaceus supplementation on cognition: A randomized, double-blind, placebo-controlled pilot study
Medicinal Mushrooms: Their Bioactive Components, Nutritional Value and Application in Functional Food Production—A Review
Neuroprotective Effects of Erinacine A on an Experimental Model of Traumatic Optic Neuropathy
Hericerin derivatives activates a pan-neurotrophic pathway in central hippocampal neurons converging to ERK1/2 signaling enhancing spatial memory
Erinacine S from Hericium erinaceus mycelium promotes neuronal regeneration by inducing neurosteroids accumulation
Neuroprotective Metabolites of Hericium erinaceus Promote Neuro-Healthy Aging
Preclinical Bioavailability, Tissue Distribution, and Protein Binding Studies of Erinacine A, a Bioactive Compound from Hericium erinaceus Mycelia Using Validated LC-MS/MS Method
Influence of Short-Term Consumption of Hericium erinaceus on Serum Biochemical Markers and the Changes of the Gut Microbiota: A Pilot Study
Hericium erinaceus enhances neurotrophic factors and prevents cochlear cell apoptosis in senescence accelerated mice
Hericium erinaceus has long been favored for its remarkable nutritional and health-promoting benefits, and erinacine A is the key component responsible for the neuroprotective properties of H. erinaceus. Establishing an efficient method for separating erinacine A from H. erinaceus and screening the erinacine A-enriched strains is crucial to maximizing its benefits. Herein, we first reported that high-speed counter current chromatography (HSCCC) is an effective method for separating high-purity erinacine A.
2024
Population aging has led to an increased interest in various dietary supplements in order to preserve cognitive function. The aim of our study was to examine the effects of Hericium erinaceus supplementation (HE) on cognitive function and serum levels of Brain-Derived Neurotrophic Factor (BDNF) and Neuropeptide Y (NPY). An 8-week double-blind comparative study involved 33 subjects, randomly assigned to a HE group and a placebo (P) group.
2024
Medicinal mushrooms, e.g., Lion’s Mane (Hericium erinaceus (Bull.) Pers.), Reishi (Ganoderma lucidum (Curtis) P. Karst.), Chaga (Inonotus obliquus (Ach. ex Pers.) Pilát), Cordyceps (Ophiocordyceps sinensis (Berk.) G.H. Sung, J.M. Sung, Hywel-Jones and Spatafora), Shiitake (Lentinula edodes (Berk.) Pegler), and Turkey Tail (Trametes versicolor (L.) Lloyd), are considered new-generation foods and are of growing interest to consumers. They are characterised by a high content of biologically active compounds, including (1,3)(1,6)-β-d-glucans, which are classified as dietary fibre, triterpenes, phenolic compounds, and sterols.
2023
Erinacine A (EA), a natural neuroprotectant, is isolated from a Chinese herbal medicine, Hericium erinaceus. The aim of this study was to investigate the neuroprotective effects of EA in a rat model of traumatic optic neuropathy. The optic nerves (ONs) of adult male Wistar rats were crushed using a standardized method and divided into three experimental groups: phosphate-buffered saline (PBS control)-treated group, standard EA dose-treated group (2.64 mg/kg in 0.5 mL of PBS), and double EA dose-treated group (5.28 mg/kg in 0.5 mL of PBS). After ON crush, each group was fed orally every day for 14 days before being euthanized.
2023
The traditional medicinal mushroom Hericium erinaceus is known for enhancing peripheral nerve regeneration through targeting nerve growth factor (NGF) neurotrophic activity. Here, we purified and identified biologically new active compounds from H. erinaceus, based on their ability to promote neurite outgrowth in hippocampal neurons. N-de phenylethyl isohericerin (NDPIH), an isoindoline compound from this mushroom, together with its hydrophobic derivative hericene A, were highly potent in promoting extensive axon outgrowth and neurite branching in cultured hippocampal neurons even in the absence of serum, demonstrating potent neurotrophic activity.
2023
Erinacines derived from Hericium erinaceus have been shown to possess various health benefits including neuroprotective effect against neurodegenerative diseases, yet the underlying mechanism remains unknown. Here we found that erinacine S enhances neurite outgrowth in a cell autonomous fashion. It promotes post-injury axon regeneration of PNS neurons and enhances regeneration on inhibitory substrates of CNS neurons.
2023
Frailty is a geriatric syndrome associated with both locomotor and cognitive decline, typically linked to chronic systemic inflammation, i.e., inflammaging. In the current study, we investigated the effect of a two-month oral supplementation with standardized extracts of H. erinaceus, containing a known amount of Erinacine A, Hericenone C, Hericenone D, and L-ergothioneine, on locomotor frailty and cerebellum of aged mice. Locomotor performances were monitored comparing healthy aging and frail mice. Cerebellar volume and cytoarchitecture, together with inflammatory and oxidative stress pathways, were assessed focusing on senescent frail animals.
2021
Erinacine A, derived from the mycelia of Hericium erinaceus, has attracted much attention due to its neuroprotective properties. However, very few studies have been conducted on the bioavailability, tissue distribution, and protein binding of erinacine A. This study aimed to investigate the bioavailability, tissue distribution, and protein binding of erinacine A in Sprague-Dawley rats. After oral administration (po) and intravenous administration (iv) of 2.381 g/kg BW of the H. erinaceus mycelia extract (equivalent to 50 mg/kg BW of erinacine A) and 5 mg/kg BW of erinacine A, respectively, the absolute bioavailability of erinacine A was estimated as 24.39%.
2021
Hericium erinaceus (H. erinaceus) is widely studied as a medicinal and edible fungus. Recent studies have shown that H. erinaceus has protective effects for diseases, such as inflammatory bowel disease and cancer, which are related to gut microbiota. To investigate the benefits of H. erinaceus intake on gut microbiota and blood indices in adulthood, we recruited 13 healthy adults to consume H. erinaceus powder as a dietary supplement. Blood changes due to H. erinaceus consumption were determined by routine hematological examination and characterized by serum biochemical markers.
2021
This study aimed to investigate the effects of Hericium erinaceus (HE) on auditory function. Twenty-four 9-month-old male senescence-accelerated prone 8 (SAMP8) mice were randomly and equally assigned to the control group (group A) and two groups supplemented with 215.25 (group B) or 430.5 mg/kg BW of HE (group C) for 12 weeks. Compared with group A, group C had significantly smaller threshold shifts by auditory brainstem responses at the end of study.
2020