About
Physical Characteristics
Caps:
Convex to broadly convex to plane at maturity, smooth, viscous when moist, coloration varies from golden brown to light yellow.
Gills:
Attachment adnate to adnexed, closer spacing, coloration starts light and turns darker with maturity.
Cognitive Effects
Enhanced Creativity
May stimulate abstract and creative thought processes.
Psychoactive Effects
Euphoria
Users often experience a sense of heightened happiness and well-being.
Helps With
Depression
Some studies suggest potential benefits in treating depression.
Anxiety
Can potentially reduce symptoms of anxiety in some users.
Potential Side Effects
Nausea
Common especially in raw consumption.
Headache
Can occur post-trip or during comedown.
Medicinal Chemistry
Look Alike Species
Specie: | Differences: | |
|---|---|---|
 | Psilocybe cyanescens Edibility:Psychoactive | P. cyanescens has a wavy cap and fruits in cooler temperatures. |
Specie:
Psilocybe cyanescens
Edibility:
Psychoactive
Differences:P. cyanescens has a wavy cap and fruits in cooler temperatures.
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References
Phylogenomics of the psychoactive mushroom genus Psilocybe and evolution of the psilocybin biosynthetic gene cluster
Therapeutic use of psilocybin from “magic mushrooms” is revolutionizing mental health treatment for many conditions, including depression, PTSD, and end-of-life care. However, knowledge of Psilocybe diversity and its evolutionary history is substantially incomplete. Our study presents the most extensive phylogenomic dataset across Psilocybe to date, with 23 samples derived from type specimens. Using ~3,000 single-copy gene families, we recovered a robust and well-supported phylogeny. Mapping psilocybin biosynthetic gene orthologs on the phylogeny revealed two types of gene cluster order corresponding to a deep split in the genus. Molecular dating suggests psilocybin biosynthesis arose in Psilocybe ~67 mya, concurrent with the K-Pg mass extinction event. A significant advancement in the understanding of Psilocybe evolution and psilocybin biosynthesis is presented.
2024