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About
Physical Characteristics
Caps:
Small to medium size, smooth texture, often appears slightly wrinkled, pure white coloration due to lack of pigmentation.
Gills:
Attachment adnate to adnexed, initially white but may turn slightly blue with age or damage.
Cognitive Effects
Enhanced Creativity
May stimulate abstract thinking and creativity.
Psychoactive Effects
Euphoria
Users often experience a state of euphoria and well-being.
Helps With
Depression
Some studies suggest potential benefits in treating depression.
Anxiety
Can reduce symptoms of anxiety in some users.
Potential Side Effects
Nausea
Can cause stomach discomfort and nausea.
Paranoia
High doses may lead to feelings of paranoia or anxiety.
Medicinal Chemistry
Look Alike Species
Specie: | Differences: | |
---|---|---|
![]() | Psilocybe cubensis Edibility:Psychoactive | ACW lacks pigmentation, resulting in a white cap and stem, unlike the typical brown or golden cap of common Psilocybe cubensis. |
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Specie:
Psilocybe cubensis
Edibility:
Psychoactive
Differences:ACW lacks pigmentation, resulting in a white cap and stem, unlike the typical brown or golden cap of common Psilocybe cubensis.
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References
Phylogenomics of the psychoactive mushroom genus Psilocybe and evolution of the psilocybin biosynthetic gene cluster
Therapeutic use of psilocybin from “magic mushrooms” is revolutionizing mental health treatment for many conditions, including depression, PTSD, and end-of-life care. However, knowledge of Psilocybe diversity and its evolutionary history is substantially incomplete. Our study presents the most extensive phylogenomic dataset across Psilocybe to date, with 23 samples derived from type specimens. Using ~3,000 single-copy gene families, we recovered a robust and well-supported phylogeny. Mapping psilocybin biosynthetic gene orthologs on the phylogeny revealed two types of gene cluster order corresponding to a deep split in the genus. Molecular dating suggests psilocybin biosynthesis arose in Psilocybe ~67 mya, concurrent with the K-Pg mass extinction event. A significant advancement in the understanding of Psilocybe evolution and psilocybin biosynthesis is presented.
2024