About
Physical Characteristics
Caps:
Smooth, white, sometimes with bluish tones, conical to flat as it matures
Gills:
Attachment adnate to adnexed, initially light, becoming purple-black with maturity
Cognitive Effects
Enhanced Creativity
Users report an increase in creative thought processes.
Psychoactive Effects
Euphoria
A profound sense of well-being and happiness.
Helps With
Depression
Can potentially alleviate symptoms of depression in some users.
Anxiety
May reduce anxiety levels temporarily.
Potential Side Effects
Nausea
Can occur, particularly at higher doses.
Paranoia
Some users may experience increased paranoia.
Medicinal Chemistry
Look Alike Species
Specie:
Psilocybe tampanensis
Edibility:
Psychoactive
Differences:
Cap color and slightly less robust growth.
Specie:
Psilocybe tampanensis
Edibility:
Psychoactive
Mushroom Ratings
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References
Phylogenomics of the psychoactive mushroom genus Psilocybe and evolution of the psilocybin biosynthetic gene cluster
Therapeutic use of psilocybin from “magic mushrooms” is revolutionizing mental health treatment for many conditions, including depression, PTSD, and end-of-life care. However, knowledge of Psilocybe diversity and its evolutionary history is substantially incomplete. Our study presents the most extensive phylogenomic dataset across Psilocybe to date, with 23 samples derived from type specimens. Using ~3,000 single-copy gene families, we recovered a robust and well-supported phylogeny. Mapping psilocybin biosynthetic gene orthologs on the phylogeny revealed two types of gene cluster order corresponding to a deep split in the genus. Molecular dating suggests psilocybin biosynthesis arose in Psilocybe ~67 mya, concurrent with the K-Pg mass extinction event. A significant advancement in the understanding of Psilocybe evolution and psilocybin biosynthesis is presented.
2024