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This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. ** The content on this website is for informational purposes only and is not a substitute for professional medical advice; always consult your physician regarding any medical condition. Reliance on this information is at your own risk. The use of psychedelic mushrooms is illegal in many jurisdictions and should not be undertaken without legal advice and careful consideration of the risks involved. **

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  • Psilocybe Cubensis Cubes Penis Envy 6
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Last updated: Oct 20, 2026

Psilocybe CubensisPenis Envy 6

"Cubes, B+"

Psilocybe Cubensis Cubes close up
Psilocybe Cubensis fruiting bodies

Scientific Classification

Kingdom:Fungi
Division:Basidiomycota
Class:Agaricomycetes
Order:Agaricales
Family:Hymenogastraceae
Genus:Psilocybe
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Frequently Asked Questions

What is the Penis Envy 6 strain?
Penis Envy 6 is a documented mushroom strain of Cubes (Psilocybe Cubensis). It is cataloged in the ShroomSpy mycology database with strain-specific characteristics, origin, and identification details.
What kind of strain is Penis Envy 6?
Penis Envy 6 is a hybrid strain produced by crossing two or more parent strains. Strain classification influences growth characteristics, potency, and visual identification.
What lineage does Penis Envy 6 belong to?
Penis Envy 6 is classified within the Penis Envy lineage. Phylogenetic clustering helps growers and researchers compare strain genetics across the Cubes family.
Is Cubes edible?
edible
Is Cubes psychoactive?
Cubes is documented as a psychoactive species. It contains psychoactive compounds that may produce mind-altering effects. Laws governing possession and use vary by jurisdiction.
What effects does Cubes produce?
Cubes is associated with the following effects: Creativity. Individual experiences vary based on dose, set, and setting.
What is the scientific classification of Cubes?
Cubes belongs to the kingdom Fungi, division Basidiomycota, class Agaricomycetes, order Agaricales, family Hymenogastraceae, genus Psilocybe. Its scientific name is Psilocybe Cubensis.
Is Cubes a naturally occurring species or a cultivated strain?
Cubes is a hybrid strain. It was created by crossing two or more parent strains.

About

Penis Envy #6 (often abbreviated as PE6) is a hybrid variant of Psilocybe cubensis, created by crossing the Penis Envy strain with a traditional cubensis strain. The result is a mushroom that combines high potency with more consistent fruiting and larger yields, making it one of the most popular strains among cultivators and psychonauts seeking a powerful yet manageable experience.

History

The original Penis Envy strain is famous for its unique morphology and strong effects but is notoriously difficult to cultivate. To improve its practicality, PE6 was developed (allegedly by mycologist John W. Allen and collaborators) by crossing it with a standard P. cubensis. This variant preserves much of the visual intensity and mental depth of classic Penis Envy while being easier to grow, faster to colonize, and producing more spores—an important trait for propagation.

Today, PE6 is widely respected for offering a balanced experience: spiritual and introspective, but less overwhelming than its parent strain.

Overview

PE6 mushrooms display thick, bulbous stems and moderately large caps, often more open and circular than the original Penis Envy. The coloration ranges from golden to caramel brown. They bruise blue intensely, indicating high levels of psilocybin and psilocin. Unlike the original PE, PE6 can drop viable spores, making it a preferred choice for cultivators.

Effects are described as deeply visual, introspective, and emotionally significant, often accompanied by body tingles and a sense of unity or revelation. It's a popular strain for both ceremonial use and recreational exploration, providing a potent but more forgiving trip.

Physical Characteristics

Caps:

Conical, falic-shaped

Gills:

Narrow to slightly enlarged in the center, pallid and grayish

Cognitive Effects

Creativity

Many individuals report heightened creativity and a sense of increased ideational fluency while under the influence of psilocybin. This may include enhanced problem-solving abilities, novel insights, and out-of-the-box thinking.

Psychoactive Effects

Hallucinogenic

Induces hallucinations - seeing, hearing, or feeling sensations that seem real but are not.

Euphoric

Creates intense feelings of happiness or excitement

Perceptual

Changes in time perception, spatial perception, and perception of one's own body

Pharmacology

Helps With

Depression

Provides relief from feelings of severe despondency and dejection

Anxiety

Helps to alleviate feelings of worry, fear, and unease

Addiction

Helps to overcome dependence on a particular substance, thing, or activity

PTSD

Helps to alleviate symptoms of post-traumatic stress disorder

OCD

Helps to alleviate symptoms of obsessive-compulsive disorder

ADD ADHD

Helps to alleviate symptoms of attention deficit disorder and attention deficit hyperactivity disorder

Pain

Microdosing psilocybin has been shown to help with certain types of pain

Migraines

Research shows that psilocybin, the active compound in magic mushrooms, has potential therapeutic benefits for migraines. A small-scale study conducted by Yale School of Medicine found that a single dose of psilocybin reduced the likelihood of having a migraine attack in two weeks.

Possible Side Effects

Nausea

Can cause discomfort or distress in the stomach accompanied by an urge to vomit

Paranoid

Induces an extreme, irrational distrust of others

Grow at Home

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Chemical Constituents

Medicinal Chemistry

Similar Species

No image

Species:

Key Differences: Galerina marginata has a more brownish cap and does not bruise blue like Psilocybe cubensis.

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Species:

Key Differences: Galerina marginata has a more brownish cap and does not bruise blue like Psilocybe cubensis.

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References

  1. Kilmer, B., Priest, M., Ramchand, R., Rogers, R. C., Senator, B., & Palmer, K. (2024). Considering Alternatives to Psychedelic Drug Prohibition. RAND Corporation.
  2. Bhagavan, C., Kanaan, R., Carter, O., Nielsen, G., Berlowitz, D., Issak, S., Braat, S., Zaloumis, S., Attard, Z., Oliver, G., Mayne, D., McKernon, D., Roebuck, G., Rucker, J., Butler, M., & Bryson, A. (2024). Psilocybin and motor function: A triple-blind, dose-finding study in healthy participants. Psychiatric Research and Clinical Practice, 6(4), 164-174. https://doi.org/10.1176/appi.prcp.20240047
  3. Nayak, S., White, S., Hilbert, S., Lowe, M., Jackson, H., Griffiths, R., Garcia-Romeu, A., & Yaden, D. (2024). Psychedelic Experiences Increase Mind Perception but do not Change Atheist-Believer Status: A Prospective Longitudinal Study. Journal of Psychoactive Drugs, 57(3), 275-284. https://doi.org/10.1080/02791072.2024.2346130
  4. Neumann, J., Dimov, K., Azatsian, K., Hofmann, B., & Gergs, U. (2024). Effects of psilocin and psilocybin on human 5-HT4 serotonin receptors in atrial preparations of transgenic mice and humans. Toxicology Letters, 398, 55-64. https://doi.org/10.1016/j.toxlet.2024.06.006
  5. Khajavinia, A., Michel, D., Ezeaka, U., Purves, R., Laprairie, R., & El-Aneed, A. (2024). Addressing a major interference in the quantification of psilocin in mouse plasma: Development of a validated liquid chromatography tandem mass spectrometry method. Journal of Chromatography A, 1730, 465123. https://doi.org/10.1016/j.chroma.2024.465123
  6. Hudspeth, J., Rogge, K., Dörner, S., Müll, M., Hoffmeister, D., Rupp, B., & Werten, S. (2024). Methyl transfer in psilocybin biosynthesis. Nature Communications, 15(1). https://doi.org/10.1038/s41467-024-46997-z
  7. Seibold, P., Dörner, S., Fricke, J., Schäfer, T., Beemelmanns, C., & Hoffmeister, D. (2024). Genetic regulation of L-tryptophan metabolism in Psilocybe mexicana supports psilocybin biosynthesis. Fungal Biology and Biotechnology, 11(1). https://doi.org/10.1186/s40694-024-00173-6
  8. Kryskow, P., Stamets , P., La Torre, J., Sattler, K., Tsang, V. W., & Williams, M. (2024). The mushroom was more alive and vibrant”: Patient reports of synthetic versus organic forms of psilocybin. .
  9. Bradshaw, A. ., Ramírez-Cruz, V., & Dentinger , B. (2024). Phylogenomics of the psychoactive mushroom genus Psilocybe and evolution of the psilocybin biosynthetic gene cluster. .
  10. Gold, E. (2023). Psilocybin Mushrooms of Australia. United States: Independently published.