
About
Physical Characteristics
Caps:
Bulbous, often lacking a pronounced umbo, smooth, bruise bluish when damaged.
Gills:
Adnate to adnexed, close, initially light brown, darkening with maturity.
Cognitive Effects
Enhanced Creativity
Users report an increase in creative thought processes.
Psychoactive Effects
Euphoria
A profound sense of well-being and happiness.
Helps With
Depression
May alleviate symptoms of depression in some users.
PTSD
Potential to help with post-traumatic stress disorder symptoms.
Potential Side Effects
Nausea
Common, especially at the onset of effects.
Anxiety
Can occur, particularly in unfamiliar or uncomfortable settings.
Medicinal Chemistry
Look Alike Species

Specie:
Psilocybe tampanensis
Edibility:
Psychoactive
Differences:
Smaller, truffle-like appearance, less potent.

Specie:
Psilocybe tampanensis
Edibility:
Psychoactive
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References
A whole genome atlas of 81 Psilocybe genomes as a resource for psilocybin production.
The Psilocybe genus is well known for the synthesis of valuable psychoactive compounds such as Psilocybin, Psilocin, Baeocystin and Aeruginascin. The ubiquity of Psilocybin synthesis in Psilocybe has been attributed to a horizontal gene transfer mechanism of a ~20Kb gene cluster. A recently published highly contiguous reference genome derived from long read single molecule sequencing has underscored interesting variation in this Psilocybin synthesis gene cluster. This reference genome has also enabled the shotgun sequencing of spores from many Psilocybe strains to better catalog the genomic diversity in the Psilocybin synthesis pathway. Here we present the de novo assembly of 81 Psilocybe genomes compared to the P.envy reference genome. Surprisingly, the genomes of Psilocybe galindoi, Psilocybe tampanensis and Psilocybe azurescens lack sequence coverage over the previously described Psilocybin synthesis pathway but do demonstrate amino acid sequence homology to a less contiguous gene cluster and may illuminate the previously proposed evolution of psilocybin synthesis.
2021