The Magic Of Adaptogens Series: Energizing Effects Of Cordyceps
on 05/05/2025
Unlock Natural Energy with Cordyceps: Explore its adaptogenic benefits. Boost Energy, Reduce Stress and Increase Libido. What more could one ask for?
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References
A review on polysaccharide biosynthesis in Cordyceps militaris
Protective effect of Cordyceps sinensis against diabetic kidney disease through promoting proliferation and inhibiting apoptosis of renal proximal tubular cells
Apoptotic effect of cordycepin on A549 human lung cancer cell line
Selective extraction of cordycepin from Cordyceps militaris – optimisation, kinetics and equilibrium studies
Structure and hypoglycemic activity of a novel exopolysaccharide of Cordyceps militaris
Cordycepin: a bioactive metabolite with therapeutic potential
Biomass and Cordycepin Production by the Medicinal Mushroom Cordyceps militaris—A Review of Various Aspects and Recent Trends towards the Exploitation of a Valuable Fungus
Cordyceps militaris (L.) Link Fruiting Body Reduces the Growth of a Non-Small Cell Lung Cancer Cell Line by Increasing Cellular Levels of p53 and p21
Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Medicinal Fungus Cordyceps with Its Nutraceutical and Therapeutic Potential
Impact of different fermentation characteristics on the production of mycelial biomass, extra-cellular polysaccharides, intra-cellular polysaccharides, and on the antioxidant activities of Cordyceps militaris (L.) Fr. (strains AG-1, PSJ-1)
Cordyceps militaris (C. militaris) is an edible parasitic fungus with medicinal properties. Its bioactive polysaccharides are structurally diverse and exhibit various metabolic and biological activities, including antitumor, hypoglycemic, antioxidant, hypolipidemic, anti-inflammatory, immunostimulatory, and anti-atherosclerotic effects. These properties make C. militaris-derived polysaccharides a promising candidate for future development. Recent advancements in microbial fermentation technology have enabled successful laboratory cultivation and extraction of these polysaccharides. These polysaccharides are structurally diverse and exhibit various biological activities, such as immunostimulatory, antioxidant, antitumor, hypolipidemic, and anti-atherosclerotic effects.
2024
This study demonstrates the nephroprotective effects of Cordyceps sinensis, which functions via promoting proliferation and inhibiting apoptosis of renal proximal tubular cells, likely targeting VEGFA and PTEN. Furthermore, the AKT and ERK signaling pathway may be critical.
2023
Cordycepin, an active ingredient in the insect fungus Cordyceps militaris, is in a category of compounds that exhibit significant therapeutic activity. The aim of the present study was to investigate the effect of cordycepin on cell proliferation, apoptosis, and cell cycle in A549 human lung cancer cells. MTT assay was used to evaluate the cytotoxic effect of cordycepin on A549 cell growth. Apoptotic effect was observed using cell morphology, DAPI staining, and DNA fragmentation studies.
2022
Cordycepin was separated successfully from Cordyceps militaris using extraction with a mixture of ethanol and water. Optimum temperature, composition of ethanol in water, solvent/solid ratio and pH of solvent were determined by a central composite design (CCD) with respect to extraction yield. The highest yield for cordycepin (96%) was predicted by the regression model and validated by comparison with the experimental results, showing good agreement.
2022
A novel neutral exopolysaccharide (EPS-III) was isolated from culture broth of Cordyceps militaris (C. militaris). The EPS-III was a homogeneous polysaccharide with Mw of 1.56 x 10(3) kDa. The yield of EPS-III from culture broth was 123.2 +/- 3.1 mg/L and the sugar content was 93.32 +/- 0.87%. The backbone of EPS-III was mainly consisted of –>4)-alpha-D-Galp-(1–>, while –>3, 6)-alpha-D-Manp-(1–>, –>4)-alpha-D-Manp-(1–>, –>3)-beta-D-Galp-(1–> and –>3)-alpha-D-Glcp-(1–> were distributed in the backbone or in the branch chains. The EPS-III had helix structure when dissolved in weak alkaline solution. It also had branched and intertwined form on the surface. The inhibition of alpha-glucosidase significantly increased as the increase of purity of exopolysaccharides.
2021
Cordycepin (3′-deoxyadenosine) is a derivative of the nucleoside adenosine, differing from the latter by the absence of oxygen in the 3′ position of its ribose part. It was initially extracted from the rare parasitic fungus Cordyceps militaris and has now been synthesized.
2021
This review presents the main factors that influence the generation of biomass and metabolites by C. militaris. It outlines physiological and genetic factors that increase or reduce the manifestation of strain degeneration in C. militaris.
2021
The fruiting body of Cordyceps militaris (L.) Link, a well-known traditional medicinal mushroom, has been used in Korea for a long time to maintain health and longevity. The present study evaluated the inhibitory effects of the fruiting body of Cordyceps militaris on the growth of the non-small cell lung cancer cell line, NCI-H460
2021
Over the past few years, people have shown confidence and trust in naturally occurring food-based products such as nutraceuticals for the treatment or management of various chronic diseases. Medicinal mushrooms have been proved to be very effective against numerous serious ailments. Cordyceps, some of the most important medicinal mushrooms, have been in use in the traditional Chinese medicine system since a long time ago. They are considered an excellent reservoir of various bioactive components, of which cordycepin is believed to have the most nutraceutical potential. Based on several research reports, cordycepin indicates its nutraceutical values by showing possible therapeutic activity against various diseases by modulating a number of cellular signaling pathways due to its redox behavior.
2020
The mycelial biomass, antioxidant activity and production of extra- and intra-cellular polysaccharides production [EPS, IPS] of Cordyceps militaris strains AG-1, PSJ-1 were evaluated under different submerged liquid culture (SLC) conditions. At 24 0 C mycelial biomass and polysaccharide production of AG-1, PSJ-1 was optimal using PVC media and static culture conditions.
2020
Comments
I’ve been diving into the world of adaptogens lately, and I have to say, Cordyceps has really caught my attention. I love how it’s not just about boosting energy but also enhancing endurance. I recently tried a Cordyceps supplement before my morning workout, and wow, I felt like I could go for miles! It’s fascinating how these fungi can help our bodies adapt to stress and improve overall performance. Plus, the fact that they’ve been used in traditional medicine for centuries adds to their credibility. I’m curious, have you tried incorporating Cordyceps into your routine? I’d love to hear about your experience or any recipes you might have! It’s amazing how something so small can have such a big impact on our health. Looking forward to hearing your thoughts!