The Magic Of Adaptogens Series: Exploring Cognitive Enhancers Lions Mane And Turkey Tail
By Zaky J on 10/25/2023
Could Lion's Mane and Turkey Tail be the Key to a Sharper Mind and a Healthier Body? The Adaptogen Series will look into these questions...
Meet Lion's Mane and Turkey Tail
In our final installment of The Magic of Adaptogens series, let's discover the extraordinary Lion's Mane and Turkey Tail mushrooms. These aren't your regular cooking mushrooms, they're superfoods known for boosting brain power and immunity!
Lion's Mane: Brain Booster
Lion's Mane looks like a white, shaggy mass rather than a typical mushroom, but don't be fooled by its appearance. This mushroom is known for improving memory, boosting creativity, and helping with concentration.
Science Spotlight: How Lion's Mane Works
Lion's Mane is special because it helps your brain produce more of a substance called Nerve Growth Factor (NGF). NGF is like a superhero for your brain cells, keeping them healthy and working well. Without enough NGF, our brains might struggle with memory and learning.
Turkey Tail: Immune Powerhouse
Turkey Tail, named for its colorful, fan-like appearance, is famous for its immune-boosting properties. This mushroom could be your best friend during cold and flu season!
Science Spotlight: How Turkey Tail Works
Turkey Tail is packed with antioxidants, which are like the body's cleaning crew. They help protect our cells from harmful substances called free radicals. These antioxidants keep your immune system strong, ready to defend your body against illnesses.
How Can You Benefit From These Mushrooms?
Adding Lion's Mane and Turkey Tail to your diet can be as simple as taking a supplement or brewing a tea. Both are available in various forms such as powders, capsules, and tinctures.
Conclusion: Harness the Power of Lion's Mane and Turkey Tail
So, are you ready to boost your brainpower with Lion's Mane and strengthen your immunity with Turkey Tail? Remember, just as superheroes need rest, so do our bodies. Ensure you use these super-mushrooms responsibly and in moderation.
Thank you for joining us on our journey and check out the next installment of The Magic of Adaptogens series. As we wrap up, let's remember that these incredible mushrooms, while powerful, are not a replacement for a balanced lifestyle and medical care when needed. Stay healthy, and keep exploring the magical world of adaptogens!
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References
Effect of erinacine A-enriched Hericium erinaceus supplementation on cognition: A randomized, double-blind, placebo-controlled pilot study
The chemical structures, biosynthesis, and biological activities of secondary metabolites from the culinary-medicinal mushrooms of the genus Hericium: A review
Medicinal Mushrooms: Their Bioactive Components, Nutritional Value and Application in Functional Food Production—A Review
Neuroprotective Effects of Erinacine A on an Experimental Model of Traumatic Optic Neuropathy
Hericerin derivatives activates a pan-neurotrophic pathway in central hippocampal neurons converging to ERK1/2 signaling enhancing spatial memory
Erinacine S from Hericium erinaceus mycelium promotes neuronal regeneration by inducing neurosteroids accumulation
Acute Effects of Naturally Occurring Guayusa Tea and Nordic Lion’s Mane Extracts on Cognitive Performance
New isoindolinone derivatives isolated from the fruiting bodies of the basidiomycete Hericium coralloides
The ethnopharmacology, phytochemistry and pharmacology of the genus Hericium
Benefits of Erinacines from Different Cultivate Formulas on Cognitive Deficits and Anxiety-Like Behaviour in Mice with Trimethyltin-Induced Toxicity
Population aging has led to an increased interest in various dietary supplements in order to preserve cognitive function. The aim of our study was to examine the effects of Hericium erinaceus supplementation (HE) on cognitive function and serum levels of Brain-Derived Neurotrophic Factor (BDNF) and Neuropeptide Y (NPY). An 8-week double-blind comparative study involved 33 subjects, randomly assigned to a HE group and a placebo (P) group.
2024
Fungal phytochemicals derived from higher fungi, particularly those found in the culinary-medicinal fungi Hericium, have gained importance in drug discovery and healthcare. This review aims to provide a comprehensive summary of the chemical structures, biosynthesis, biological activities, and pharmacological properties of monomer compounds derived from Hericium.
2024
Medicinal mushrooms, e.g., Lion’s Mane (Hericium erinaceus (Bull.) Pers.), Reishi (Ganoderma lucidum (Curtis) P. Karst.), Chaga (Inonotus obliquus (Ach. ex Pers.) Pilát), Cordyceps (Ophiocordyceps sinensis (Berk.) G.H. Sung, J.M. Sung, Hywel-Jones and Spatafora), Shiitake (Lentinula edodes (Berk.) Pegler), and Turkey Tail (Trametes versicolor (L.) Lloyd), are considered new-generation foods and are of growing interest to consumers. They are characterised by a high content of biologically active compounds, including (1,3)(1,6)-β-d-glucans, which are classified as dietary fibre, triterpenes, phenolic compounds, and sterols.
2023
Erinacine A (EA), a natural neuroprotectant, is isolated from a Chinese herbal medicine, Hericium erinaceus. The aim of this study was to investigate the neuroprotective effects of EA in a rat model of traumatic optic neuropathy. The optic nerves (ONs) of adult male Wistar rats were crushed using a standardized method and divided into three experimental groups: phosphate-buffered saline (PBS control)-treated group, standard EA dose-treated group (2.64 mg/kg in 0.5 mL of PBS), and double EA dose-treated group (5.28 mg/kg in 0.5 mL of PBS). After ON crush, each group was fed orally every day for 14 days before being euthanized.
2023
The traditional medicinal mushroom Hericium erinaceus is known for enhancing peripheral nerve regeneration through targeting nerve growth factor (NGF) neurotrophic activity. Here, we purified and identified biologically new active compounds from H. erinaceus, based on their ability to promote neurite outgrowth in hippocampal neurons. N-de phenylethyl isohericerin (NDPIH), an isoindoline compound from this mushroom, together with its hydrophobic derivative hericene A, were highly potent in promoting extensive axon outgrowth and neurite branching in cultured hippocampal neurons even in the absence of serum, demonstrating potent neurotrophic activity.
2023
Erinacines derived from Hericium erinaceus have been shown to possess various health benefits including neuroprotective effect against neurodegenerative diseases, yet the underlying mechanism remains unknown. Here we found that erinacine S enhances neurite outgrowth in a cell autonomous fashion. It promotes post-injury axon regeneration of PNS neurons and enhances regeneration on inhibitory substrates of CNS neurons.
2023
The aim of this study was to assess the effects of guayusa extract and Nordic Lion’s Mane (LM) on cognition. Using a randomized, double-blind, placebo-controlled, crossover design, we examined the effects of a single dose of 650 mg guayusa extract (AMT: AmaTea® Max) vs. 1 g Nordic-grown Lion’s Mane (LM) vs. placebo (PL). Participants attended three testing visits consisting of neuropsychological tests (Go/No-go, N-Back, and Serial 7 s tasks) assessing performance, subjective assessments of cognitive perception, and vital signs. Each assessment was measured at baseline (pre-ingestion) and 1 and 2 h post ingestion.
2023
Preparative high-performance liquid chromatography (HPLC) purification of the ethyl acetate extract derived from dried basidiomes of the European mushroom Hericium coralloides led to the identification of two previously undescribed isoindolinone derivatives named corallocins D and E (1–2). The structures of the compounds were elucidated based on HR-ESI-MS (high-resolution electron spray ionization mass spectrometry), interpretation of 1D and 2D NMR spectra, electronic circular dichroism (ECD) experiments, and comparisons with published and theoretical data.
2023
Mushrooms in the genus Hericium are used as functional food and traditional medicines for a long history in East Asian countries such as China, India, Japan, and Korea. Some species of Hericium are called as monkey head mushroom (Houtougu) in China and Yamabushitake in Japan, which are traditionally considered as rare and precious health promoting food and medicinal materials for the treatment of dyspepsia, insomnia, chronic gastritis, and digestive tract tumors.
2023
We investigated the neurological effects of the varied erinacine composition of different mycelia cultures in mice with trimethyltin (TMT)-induced neurodegeneration. Forty male ICR mice were randomly divided into five groups of Sham-veh, TMT-veh, TMT-EME, TMT-EMR and TMT-EME/R. The TMT groups received 2.6 mg/kg one-time intraperitoneal injections of TMT. Oral dosages of 200 mg/kg erinacine combination from each Hericium erinaceus mycelia (EM) cultivated formula (100% eucalyptus wood [E], 100% rubber wood [R], or 40% eucalyptus wood/60% rubber wood [E/R]) were given for two weeks.
2023
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