Phellinus Linteus

Phellinus Linteus

Common Names: Mesima, Sanghwang, Meshimakobu

Medicinal

About

Phellinus linteus, conocido como Mesima, es un hongo medicinal utilizado en la medicina tradicional asiática para tratar diversas enfermedades. Contiene polisacáridos y otros compuestos que exhiben efectos inmunomoduladores, anticancerígenos y antioxidantes. La Mesima causa una pudrición blanca en los morales y ha sido utilizada durante siglos en la medicina coreana y japonesa.

Flavors

Amargo

Phellinus linteus se describe a menudo como de sabor amargo, lo cual es una de las razones por las que no se utiliza típicamente en platos culinarios.

Textures

Difícil

El cuerpo fructífero de Mesima es duro y resistente.

Woody

Debido a su hábito de crecimiento y naturaleza, su textura es leñosa y no es adecuada para preparaciones culinarias típicas.

Fragrances

Terroso

Phellinus linteus tiene un aroma natural terroso.

Woody

Dado su crecimiento en raíces de árboles viejos, a veces puede tener un aroma ligeramente amaderado.

Physical Characteristics

Caps:

Con forma de pezuña, de hasta 15 cm de ancho. De color marrón amarillento a negro.

Gills:

Poros de color amarillo-marrón, 5-6 por mm.

Helps With

Cáncer

Demostrado para inducir apoptosis en células cancerosas e inhibir el crecimiento tumoral.

Inmunidad

Estimula la actividad de linfocitos y macrófagos

Inflamación

Exhibe efectos antiinflamatorios al inhibir TNF-alfa, IL-6 y óxido nítrico.

Medicinal Chemistry

Similar Species

Phellinus Ribis

Species: Phellinus ribis

Edibility: no comestible

Key Differences: Crece en una variedad de árboles, causa lesiones de chancro.

Mushroom Ratings

4.0

Based on 1 Review

5

4

3

2

1


Share your thoughts

If you've consumed this mushroom, share your thoughts with our community

Transformative Benefits of Phellinus linteus-Mesima for Mind and Body

01/29/2025

Sam Matterson

CalmContentFocusEnduranceEnergySpiritualDizzy
As an avid enthusiast of natural remedies, I recently discovered Phellinus linteus-Mesima mushrooms and they have truly transformed my wellness routine. After just a few weeks of incorporating these into my diet, I've experienced a remarkable increase in my focus and overall energy levels. The mushroom's unique properties appear to support cognitive function, which has been particularly beneficial for my chronic struggles with distraction. The calming effects have also enhanced my ability to manage stress, making me feel more centered and reflective throughout my day. I find that when I consume them in powdered form, whether in smoothies or as a tea infusion, they deliver the perfect balance of mental clarity and relaxation. While I am grateful for the benefits, I did want to note that I occasionally felt slight dizziness, so I ensure I stay hydrated. Overall, Phellinus linteus-Mesima has become an essential part of my lifestyle, particularly aiding my anxiety management and promoting better sleep patterns. I highly recommend this mushroom for anyone looking to enhance their mental and physical health naturally. Its versatility makes it an excellent addition for those exploring the power of fungi in their wellness journey.

References


  • Effects of hispolon on glioblastoma cell growth

  • Hispolon is a polyphenolic compound isolated from <i>Phellinus linteus</i> which exhibits antitumor activity. Here, we explored the effects of hispolon on human glioblastoma cells U87MG. Cell viability was examined by MTT assay. Growth was investigated by incubating cells with various concentrations of hispolon (25 and 50 microM) for 24, 48 or 72 h and daily cell count. Cell cycle and apoptosis assay were assessed by flow cytometry. Hispolon decreased cell viability in a dose- and time-dependent manner.

    2021

  • Enhanced Mycelium Production of Phellinus igniarius (Agaricomycetes) Using a He-Ne Laser with Pulsed Light

  • This study used a He-Ne laser with pulsed light irradiation to produce mutant strains of Phellinus igniarius strain JQ9 with enhanced characteristics for fermentation (17.685 ± 3.092 g/L) compared with the parent strain (12.062 ± 1.119 g/L). The combined treatment conditions were as follows: He-Ne laser irradiation for 30 min using a spot diameter of 10 mm, pulsed light treatment power set at 100 J, a treatment distance of 14.5 cm, and a flash frequency of 0.5 s. The production of bioactive polysaccharides and small biocompounds such as polyphenols, flavonoids, and triterpenes increased together with mycelium production.

    2021

  • Polysaccharide isolated from Phellinus linteus mycelia exerts anti-inflammatory effects via MAPK and PPAR signaling pathways

  • In the dimethylnitrosamine (DMN)-induced hepatic fibrosis Wistar rat model, the mycelium extract of Phellinus linteus (PLE) (20 mg/Kg) displayed significant protection against hepatic fibrosis. The present investigation characterized eleven new ionone derivatives, phellinulins D(-)N (4(-)14), from the P. linteus mycelium extract and the relative stereochemical structures were constructed according to the spectroscopic and spectrometric analytical results.

    2018

  • Hepatoprotective Principles and Other Chemical Constituents from the Mycelium of Phellinus linteus

  • In the dimethylnitrosamine (DMN)-induced hepatic fibrosis Wistar rat model, the mycelium extract of Phellinus linteus (PLE) (20 mg/Kg) displayed significant protection against hepatic fibrosis. The present investigation characterized eleven new ionone derivatives, phellinulins D(-)N (4(-)14), from the P. linteus mycelium extract and the relative stereochemical structures were constructed according to the spectroscopic and spectrometric analytical results.

    2018

  • Phellinus linteus grown on germinated brown rice increases cetuximab sensitivity of KRAS-mutated colon cancer

  • Colon cancer is one of the most common types of cancer, and it has recently become a leading cause of death worldwide. Among colon cancers, the v-ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS)-mutated form is notorious for its non-druggable features. Cetuximab, a monoclonal antibody that binds to the epidermal growth factor receptor, has been introduced as an antitumor therapy; however, secondary resistance and side effects significantly limit its effective use in these cancers. In this study, we prepared Phellinus linteus on germinated brown rice (PBR) extracts to increase the sensitivity of KRAS-mutated colon cancers to cetuximab.

    2017

  • Phellinus linteus Mycelium Alleviates Myocardial Ischemia-Reperfusion Injury through Autophagic Regulation

  • The incidence of myocardial ischemia-reperfusion (IR) injury is rapidly increasing around the world and this disease is a major contributor to global morbidity and mortality. It is known that regulation of programmed cell death including apoptosis and autophagy reduces the impact of myocardial IR injury. In this study, the cardioprotective effects and underlying mechanisms of Phellinus linteus (Berk. and Curt.) Teng, Hymenochaetaceae (PL), a type of medicinal mushroom, were examined in rats subjected to myocardial IR injury. The left main coronary artery of rats was ligated for 1 h and reperfused for 3 h.

    2017

  • Modulation of T cell response by Phellinus linteus

  • Phellinus linteus, a species of mushroom, has been shown to contribute to health benefits, such as anti-inflammatory activity and immunomodulatory efficacy. The aim of this study was to analyze the most effective constituents of P. linteus fermented broths, polysaccharides, and to evaluate their immunoregulatory effects on T cells.

    2016

  • Phellinus linteus grown on germinated brown rice suppress metastasis and Induce Apoptosis of Colon Cancer Cells by suppressing NF-kB and Wnt/ß-catenin Signaling Pathways

  • Phellinus linteus is a mushroom with a variety of biological functions, such as antitumor and immunomodulating activities. P. linteus grown on germinated brown rice (PBR) feeding significantly decreased colon cancer metastasis to the lung and overall tumor size. In biomarker analysis, PBR showed significant anti-metastatic, anti-proliferative and pro-apoptotic activities. Detailed mechanistic studies highlighted that PBR strongly modulated MMP-2 and -9 activities and apoptotic biomarkers as well as decreased NF-κB, β-catenin, and mitogen-activated protein kinase (MAPK) expression. Together, these findings suggest that PBR is effective in preventing CRC by suppressing metastasis and proliferation and inducing apoptosis.

    2015

  • A novel polysaccharide from mycelia of cultured Phellinus linteus displays antitumor activity through apoptosis

  • Two novel polysaccharides termed PLPS-1 and PLPS-2 were isolated from mycelia of cultured Phellinus linteus by hot water extraction, purified by DEAE-52 cellulose and Sephadex G-100 column chromatography, and structurally characterized by FTIR and NMR spectroscopy, GC-MS, periodate oxidation/ Smith degradation, and methylation analysis. The monosaccharide compositions of PLPS-1 (MW 2.5×105 Da) and PLPS-2 (MW 2.8×104 Da) were respectively Glc, Ara, Fuc, Gal, and Xyl in molar ratio 21.964: 1.336: 1.182: 1: 1, and Glc, Gal, Man, Ara, Fuc, Xyl in molar ratio 14.368: 2.594: 1.956: 1.552: 1.466: 1; i.e., both were heteropolysaccharides.

    2015

  • Anti-inflammatory activity of mushroom-derived hispidin through blocking of NF-kappaB activation

  • Hispidin, a polyphenol compound mainly derived from the valuable medicinal mushroom <i>Phellinus</i> species, has been found to possess distinct biological effects. However, the anti-inflammatory potential of hispidin still remains uncharacterized. RESULTS: In this study, the effects of hispidin on activation of nuclear factor kappa B (NF-kappaB) and the subsequent production of inducible nitric oxide synthase (iNOS) were determined in the lipopolysaccharide (LPS)-induced macrophage RAW 264.7 cells. Our data indicated that hispidin inhibits transcriptional activity of NF-kappaB in a dose-dependent manner. Hispidin also attenuated LPS-induced NF-kappaB nuclear translocation and associated inhibitor of kappa B (IkappaB-alpha) degradation.

    2015